Avista Capital Partners-Backed Company to Continue Add-On Acquisition Strategy
Sayreville, NJ, March 24, 2014 – Vertical Pharmaceuticals, LLC, a wholly owned subsidiary of Vertical /
Trigen Holdings, LLC (“Vertical / Trigen”), today announced that it has acquired the rights to three
branded women’s health products from Upsher-Smith Laboratories, Inc. The terms of the transaction
were not disclosed. Vertical / Trigen is a portfolio company of Avista Capital Partners.
The acquisition complements and further diversifies Vertical Pharmaceuticals’ existing women’s health
franchise. The acquired products include: Divigel® (estradiol gel) 0.1%; Nexa® Plus, a branded line of
prenatal vitamins; and Provella®, a women’s health focused probiotic dietary supplement. As part of the
transaction, Upsher-Smith has transferred the New Drug Application (NDA) for Divigel® to Vertical
Pharmaceuticals. The products will be marketed by Vertical Pharmaceuticals’ dedicated women’s health
“We are very excited to be expanding our position in the growing field of women’s health,” said Steven
Squashic, CEO of Vertical / Trigen. “With these additions to our portfolio, we will be able to drive
efficiencies through enhanced scale and further optimize our commercial infrastructure. We are
confident that our highly experienced women’s health sales force will enable us to reach more patients
and caregivers with these products.”
“This is a positive first step in our strategy to expand the Vertical / Trigen platform through add-on
acquisitions,” said Brian Markison, Executive Chairman of Vertical / Trigen and Healthcare Industry
Executive of Avista. “We will continue to pursue additional opportunities to acquire complementary
assets in order to broaden our portfolio of high-quality products and accelerate the Company’s growth.”
Important Safety Information for Divigel®
What is the most important information I should know about Divigel® (an estrogen hormone)?
- Using estrogen-alone increases your chance of getting cancer of the uterus (womb). Report any
unusual vaginal bleeding right away while you are using Divigel®. Vaginal bleeding after
menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider
should check any unusual bleeding to find out the cause.
- Do not use estrogen-alone to prevent heart disease, heart attacks, strokes or dementia (decline
of brain function)
- Using estrogen-alone may increase your chances of getting strokes or blood clots
- Using estrogen-alone may increase your chance of getting dementia, based on a study of women
65 years of age or older
- Do not use estrogens with progestins to prevent heart disease, heart attacks, strokes or
- Using estrogens with progestins may increase your chances of getting heart attacks, strokes,
breast cancer, or blood clots
- Using estrogens with progestins may increase your chance of getting dementia, based on a study
of women 65 years of age or older
- You and your healthcare provider should talk regularly about whether you still need treatment
Divigel® should not be used if you have unusual vaginal bleeding, currently have or have had certain
cancers, including cancer of the breast or uterus, had a stroke or heart attack; currently have or have
had blood clots, currently have or have had liver problems, have been diagnosed with a bleeding
disorder, are allergic to Divigel® or any of its ingredients, or think you may be pregnant.
Tell your healthcare provider about all of your medical problems and the medicines you take, if you are
going to have surgery or will be on bed rest, and if you are breastfeeding.
Call your healthcare provider right away if you get any of the following symptoms: new breast lumps,
unusual vaginal bleeding, changes in vision or speech, sudden new severe headaches, or severe pains in
your chest or legs with or without shortness of breath, weakness and fatigue.
Common side effects that may occur with Divigel® include headache; breast pain; irregular vaginal
bleeding or spotting; stomach or abdominal cramps, bloating; nausea and vomiting; hair loss; fluid
retention and vaginal yeast infection.
Serious but less common side effects include heart attack, stroke, blood clots, dementia, breast cancer,
cancer of the uterus, ovarian cancer, high blood pressure, high blood sugar, gallbladder disease, liver
problems, and enlargement of benign uterus tumors (“fibroids”).
Alcohol-based gels are flammable. Avoid fire, flame or smoking until the gel has dried.
Please see Patient Information including Boxed Warning for Divigel® at www.divigel.com.
You are encouraged to report negative side effects to the FDA by visiting www.fda.gov/medwatch or
About Vertical / Trigen
Vertical Pharmaceuticals, LLC was founded in 2003 with a mission to develop, market, and acquire
products offering therapeutic benefits for patients and healthcare providers. Vertical Pharmaceuticals
supplies niche prescription pharmaceutical preparations, specializing in women’s health and pain
management. Vertical’s prescription medications are marketed by its dedicated sales force throughout
the United States.
Trigen Laboratories, LLC is a generic pharmaceutical company offering unique products across an
increasing array of categories. Trigen seeks to bring value-driven generic products to its customers,
working vigorously with its partners to identify and develop products which face an assortment of
challenges. Additionally, Trigen identifies unique marketing opportunities and is steadfast in its pursuit
to deliver products to best serve these markets.
About Avista Capital Partners
Avista Capital Partners is a leading private equity firm with approximately $6 billion under management.
Founded in 2005, Avista makes controlling or influential minority investments in growth-oriented
energy, healthcare, communications & media, industrials, and consumer businesses. Through its team
of seasoned investment professionals and industry experts, Avista seeks to partner with exceptional
management teams to invest in and add value to well-positioned businesses.